The Neuroscience and Behavioural Disorders (NBD) Programme is focused on understanding the structure and function of the nervous system, and the neural mechanisms underlying human neurological, psychiatric and ophthalmological disorders.
The complex structure attached to the post-synaptic membrane—known as the post-synaptic density—remains largely mysterious. The Human Frontier Science Program has funded a three-year project to study post-synaptic structure and function. This ambitious project aims to understand the dynamic organization of the post-synaptic scaffold, using a range of methods including: genomics, transcriptomics, proximity labelling, mass spectrometry, and neurogenetics. The Claridge-Chang Lab at Duke-NUS Medical School is seeking to appoint a Research Assistant, ideally with a strong background in molecular neuroscience, to join this project.
The candidate will be involved in conducting research activities, including (but not limited to): planning; organising; conducting; and communicating research studies within the overall scope of one or more research projects. The duties will include but not limited to the following: –
- Collect, analyse and interpret experimental results.
- Write draft of research papers and review articles.
- Assist to provide guidance and support to other researchers, as well as undergraduate and graduate students. Occasional educational/instructional activities.
- Maintain housekeeping of the laboratory area, general maintenance tasks and animal stock maintenance.
- Responsible for laboratory safety.
- Order/prepare common reagents and maintain lab inventory.
- Perform other related duties incidental to the work described therein.
- Bachelor’s Degree in biological sciences or related field, and a keen interest in neuroscience.
- Has excellent written and oral communication skills
- Experience in scientific sourcing & procurement.
- Has laboratory experimental skills, including the relevant skill set to perform the following techniques: mouse experiments; cell culture; biochemistry; transfection; molecular biology (subcloning methods including restriction digests, PCR and gel electrophoresis); biochemical analysis; bioinformatic data analysis.
- Skills in microscopy: e.g. laser confocal microscopy, image analysis (ImageJ, Zeiss LSM Browser, PhotoShop, Metamorph and/or Matlab) and neuroanatomical analysis (e.g. Neurolucida, FIJI, NBLAST).
- Skills in bioinformatic data analysis: Python, R, or similar analysis methods.
- A self-motivated individual who is able to work independently, prioritise, multi-task and work collaboratively in a research environment of a diverse workforce.
Please email a CV and cover letter to claridge-chang.adam<at>duke-nus.edu.sg.
We regret that only shortlisted candidates will be notified.