by Caroline Wee, the SfN.SG Chapter’s Director of Seminars
On Wednesday, 19th November 2022, the Brain & Body Seminar Series for the year 2022 was kicked off by Professor Gary Patti from Washington University in St. Louis. He presented an engaging talk on “Understanding the Cell-Intrinsic and Cell-Extrinsic Drivers of Oncogenesis”. As he was talking to an audience with a mixed background, he began with a discussion on the challenges of metabolomics, followed by a description of how such a powerful technology can be used to dissect both cellular cancer mechanisms such as the Warburg effect, as well as global effects such as the metabolic consequences of tumours on whole-body physiology (including but not limited to the brain!). Prof. Patti also illustrated how the zebrafish model can be leveraged to understand tumour-liver metabolic cross-talk, which involves an interplay between amino acid and glucose metabolism. The Q&A session was also extremely lively, taking up over 20 minutes, and spanning a wide range of topics, from discussions on the mechanisms of metabolic flux regulation to potential therapeutic strategies. function.
The Brain & Body Seminar Series continues with the next installment in a month’s time. We are looking forward to Professor Monica Dus on the 23rd of November, who will share her research on nutrigenomic effects on taste and food intake in fruitflies and mammals. Please register for this talk now, by clicking this link.
If you missed the seminar, the video recording can be found here:
Passcode: members, please write to Dr Xu Sangyu to receive the passcode.